Olfactory Smell Dysfunction in Type 2 Diabetes Mellitus


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The increasing global prevalence of diabetes mellitus presents a major challenge for health systems today. Although diabetic retinopathy, nephropathy and neuropathy are well-established complications of diabetes, there is a paucity of research examining the impact of dysglycemia on the olfactory system. Smell is an important sense, it plays a role in the safety, nutrition and quality of life of an individual, but its importance is often overlooked when compared to the other senses.
As with all our senses, our sense of smell can get worse with age. It is estimated that 24 percent of older adults in the US UU They have olfactory dysfunction, although the percentage of people who encounter it with daily interference is much lower.

A decrease in the sense of smell can have dangerous consequences. However, since it can inhibit the ability to detect the presence of olfactory indicators of danger, including the smell of smoke. New research has shown that insulin resistance, caused by diabetes mellitus, is also related to the development of olfactory dysfunction.
It is not often that the sense of smell is formally evaluated in the way hearing and sight are as we get older. The research behind the decreased sense of smell is also limited, which means that the full extent of how olfaction relates to certain degenerative diseases is unknown.

The researchers in this study used data from participants older than 50 years, collected over two years of the odor evaluation from the National Nutrition and Nutrition Examination Survey (NHANES) to determine how the It relates the sense of smell with certain biological markers of diabetes mellitus (DM). The markers measured included fasting blood glucose, glycohemoglobin, serum insulin and evaluation of the homeostasis model of insulin sensitivity (HOMA-IR).

The results showed that there was an increased risk of olfactory dysfunction in the participants with DM markers of fasting blood glucose and HOMA-IR quintiles. The data suggest that insulin resistance may be a mechanism for the development of the deterioration of smell with age. The other markers measured did not seem to be connected with the reduction in the ability to smell.

The researchers claim that more research will be needed to confirm the connection between insulin resistance related to DM and olfactory dysfunction, but the correlation is clear in the results of their examination of data.

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Video credits to Free Diabetes & Health YouTube channel





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    Olfactory Smell Dysfunction in Type 2 Diabetes Mellitus

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