ABOUT THIS VIDEO:
Autophagy is the key link between CV inflammation and plaque reversion. And fasting stimulates autophagy. If the process of plate reversal is not controlled and LDL continues to be deposited in the arterial wall, mast cells and polymorphs wrinkle and die, releasing the lysosomal contents into the bloodstream, creating a risk of heart attack and accident. cerebrovascular.
What causes LDL to continuously deposit in the arterial walls? Injury to the intima / endothelium. LDL then passes through cracks and holes in the endothelium. Mast cells and leukocytes (polymorphs) then attack the plaque. Do you remember the inflammation plane?
MPO is released by the polymorphs.
Lp-PLA2 is released by mast cells.
And the MACR (micro albumin creatinine ratio) is the measure of the number of holes and cracks in the intima / endothelium.)
What causes cracks and holes in the intima / endothelium? High glucose and insulin.
Fasting and low carbohydrate diets produce prolonged periods of lower blood glucose levels and lower insulin levels. That's why they help.
This is a review of NEJM on the biochemical process of autophagy.
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ABOUT DR. BREWER
Dr. Brewer started out as an emergency doctor. After seeing too many preventable heart attacks, he went to Johns Hopkins to learn Preventive Medicine. While there, the graduate program in preventive medicine training began to run. From there, he made a career in the practice and management of preventive medicine and primary care clinics. His last role in this area was the Medical Director of Premise, which has about 1,000 primary care / prevention clinics. He was also the Medical Director of MDLIVE, the second largest telemedicine company. More recently, he founded PrevMed, a clinic for the prevention of heart attacks and strokes.
At PrevMed, we focus on heart attack, stroke and cognitive decline. We serve patients who have already experienced an event, as well as those who have not developed a diagnosis or event. Dr. Brewer provides services through telemedicine or in person if you are in the Lexington, KY area. We found a lot of pre-diabetes or undiagnosed insulin resistance. The treatment of unrecognized risk factors, such as pre-diabetes, reduces risk and prevents diseases.
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Video credits to Ford Brewer MD MPH YouTube channel